7,073 research outputs found
Non-integrality of some Steinberg modules
We prove that the Steinberg module of the special linear group of a quadratic
imaginary number ring which is not Euclidean is not generated by integral
apartments. Assuming the generalized Riemann hypothesis, this shows that the
Steinberg module of a number ring is generated by integral apartments if and
only if the ring is Euclidean. We also construct new cohomology classes in the
top dimensional cohomology group of the special linear group of some quadratic
imaginary number rings.Comment: 17 pages. To appear in Journal of Topolog
Complete recovery from anxiety disorders following Cognitive Behavioural Therapy in children and adolescents: a meta analysis
Cognitive Behavior Therapy (CBT) is a well-established treatment for childhood anxiety disorders. Meta-analyses have concluded that approximately 60% of children recover following treatment, however these include studies using a broad range of diagnostic indices to assess outcomes including whether children are free of the one anxiety disorder that causes most interference (i.e. the primary anxiety disorder) or whether children are free of all anxiety disorders. We conducted a meta-analysis to establish the efficacy of CBT in terms of absence of all anxiety disorders. Where available we compared this rate to outcomes based on absence of primary disorder. Of 56 published randomized controlled trials, 19 provided data on recovery from all anxiety disorders (n = 635 CBT, n = 450 control participants). There was significant heterogeneity across those studies with available data and full recovery rates varied from 47.6 to 66.4% among children without autistic spectrum conditions (ASC) and 12.2 to 36.7% for children with ASC following treatment, compared to up to 20.6% and 21.3% recovery in waitlist and active treatment comparisons. The lack of consistency in diagnostic outcomes highlights the urgent need for consensus on reporting in future RCTs of childhood anxiety disorders for the meaningful synthesis of data going forwards
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Improvement in Renal Function and Reduction in Serum Uric Acid with Intensive Statin Therapy in Older Patients: A Post Hoc Analysis of the SAGE Trial.
BackgroundImprovement in renal function and decreases in serum uric acid (SUA) have been reported following prolonged high-intensity statin (HMG-CoA reductase inhibitor) therapy. This post hoc analysis of the SAGE trial examined the effect of intensive versus less intensive statin therapy on renal function, safety, and laboratory parameters, including SUA, in elderly coronary artery disease (CAD) patients (65-85 years) with or without chronic kidney disease (CKD).MethodsPatients were randomized to atorvastatin 80 mg/day or pravastatin 40 mg/day and treated for 12 months. Patients were stratified using Modification of Diet in Renal Disease (MDRD) estimated glomerular filtration rates (eGFRs) in CKD (eGFR <60 mL/min/1.73 m(2)) and non-CKD populations.ResultsOf the 893 patients randomized, 858 had complete renal data and 418 of 858 (49%) had CKD (99% Stage 3). Over 12 months, eGFR increased with atorvastatin and remained stable with pravastatin (+2.38 vs. +0.18 mL/min/1.73 m(2), respectively; p < 0.0001). MDRD eGFR improved significantly in both CKD treatment arms; however, the increased eGFR in patients without CKD was significantly greater with atorvastatin (+2.08 mL/min/1.73 m(2)) than with pravastatin (-1.04 mL/min/1.73 m(2)). Modest reductions in SUA were observed in both treatment arms, but a greater fall occurred with atorvastatin than with pravastatin (-0.52 vs. -0.09 mg/dL, p < 0.0001). Change in SUA correlated negatively with changes in eGFR and positively with changes in low-density lipoprotein cholesterol. Reports of myalgia were rare (3.6% CKD; 5.7% non-CKD), and there were no episodes of rhabdomyolysis. Elevated serum alanine and aspartate transaminase to >3 times the upper limit of normal occurred in 4.4% of atorvastatin- and 0.2% of pravastatin-treated patients.ConclusionIntensive management of dyslipidemia in older patients with stable coronary heart disease may have beneficial effects on renal function and SUA
One-pot near-ambient temperature syntheses of aryl(difluoroenol) derivatives from trifluoroethanol
Difluoroalkenylzinc reagents prepared from 1-(2’-methoxy-ethoxymethoxy)-2,2,2-trifluoroethane and 1-(N,N-diethylcarbamoyloxy)-2,2,2-trifluoroethane at ice bath temperatures, underwent Negishi coupling with a range of aryl halides in a convenient one pot procedure. While significant differences between the enol acetal and carbamate reagents were revealed, the Negishi protocol compared very favourably with alternative coupling procedures in terms of overall yields from trifluoroethanol
Chandra localization of XTE J1906+090 and discovery of its optical and infrared counterparts
We present the Chandra identification and localization of the transient X-ray source XTE J1906+090 and the discovery of its optical and infrared counterparts. Our analysis of archival Chandra ACIS-I observations of the field found the source approximately 8 away from the position determined earlier with the RXTE PCA. We have confirmed the source identification with timing analysis of the X-ray data, which detected the source spin period of 89.6 s. The best Chandra position for the source is R.A. = 19h04m47491, decl. = +09024140. Subsequently, we performed optical observations of the field around the new location and discovered a coincident optical source with R-band magnitude of 18.7. A search in the Two Micron All Sky Survey catalog revealed an infrared point source with J = 15.2, H = 14.2, and K = 13.5, whose location is also coincident with our Chandra and optical positions. Our results add fresh evidence for a Be/X-ray transient nature for XTE J1906+090
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Sociodemographic Correlates of Sexlessness Among American Adults and Associations with Self-Reported Happiness Levels: Evidence from the U.S. General Social Survey
Although sexual activity is commonly believed to be a key component of emotional well-being, little is known about the factors associated with the absence of sexual activity or its associations with self-reported happiness. Using the U.S. General Social Survey–National Death Index 2008 dataset, a series of nationally representative surveys (1988–2002), this study analyzed the sociodemographic and lifestyle factors associated with past-year sexlessness and self-reported happiness among American adults (n = 17,744). After adjustment for marital status, there were no significant time trends evident in the proportion of American adults reporting past-year sexlessness. Among participants (age = 18–89 years), 15.2% of males and 26.7% of females reported past-year sexlessness while 8.7% of males and 17.5% of females reported no sex for 5 years or more. For both genders, past-year sexlessness was most strongly associated with older age and being currently non-married in the multivariable models. Among males, the multivariable analysis also showed that sexlessness was associated with providing less than 20% of the house-hold income (OR 2.27). In female participants, sexlessness was associated with very low income, poor health, lower financial satisfaction, absence of children, and having conservative sexual attitudes (OR 1.46–3.60). For both genders, Black race was associated with a much lower likelihood of sexlessness among currently non-married adults. The purported detrimental impact of sexlessness on self-reported happiness levels was not evident in this large, nationally representative study after adjusting for sociodemographic factors. Sexless Americans reported very similar happiness levels as their sexually active counterparts
Factorization of correlations in two-dimensional percolation on the plane and torus
Recently, Delfino and Viti have examined the factorization of the three-point
density correlation function P_3 at the percolation point in terms of the
two-point density correlation functions P_2. According to conformal invariance,
this factorization is exact on the infinite plane, such that the ratio R(z_1,
z_2, z_3) = P_3(z_1, z_2, z_3) [P_2(z_1, z_2) P_2(z_1, z_3) P_2(z_2,
z_3)]^{1/2} is not only universal but also a constant, independent of the z_i,
and in fact an operator product expansion (OPE) coefficient. Delfino and Viti
analytically calculate its value (1.022013...) for percolation, in agreement
with the numerical value 1.022 found previously in a study of R on the
conformally equivalent cylinder. In this paper we confirm the factorization on
the plane numerically using periodic lattices (tori) of very large size, which
locally approximate a plane. We also investigate the general behavior of R on
the torus, and find a minimum value of R approx. 1.0132 when the three points
are maximally separated. In addition, we present a simplified expression for R
on the plane as a function of the SLE parameter kappa.Comment: Small corrections (final version). In press, J. Phys.
Success factors between suppliers and customers in service outsourcing activities
This study examines the relationship between outsourcing motives, supplier-customer relationship and perceived value in non-core service outsourcing. That is, key factors responsible for supplier-customer relationship which provide customer value in service outsourcing is still unclear. A total of 1,757 companies were randomly selected for the survey. 234 valid questionnaires were returned (13.4% response rate). The structural equation method was used to obtain the best fit model. The most significant contribution of this study is that, ‘relationship interaction’ has a greater impact on customer perceived value than ‘relationship quality’ in service outsourcing. That is, customer-supplier ‘relationship interaction’ that enhances communication, cooperation, coordination, conflict resolution, and integration activities rather than ‘relationship quality’ such as loyalty and trust, would exert the greatest effect on perceived customer value
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